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Maraviroc: A Coreceptor CCR5 Antagonist for Management of HIV Infection

Grade 3 or 4 adverse events were reported in approximately 29% in the placebo and maraviroc once-daily groups and 35% in the maraviroc twice-daily group. Grade 3 or 4 elevations in hepatic ... read more

Maraviroc ( Celsentri )

Maraviroc (known by the trade name Celsentri in Europe and Selzentry in the United States) remains the only drug to be licensed from a class of antiretrovirals called CCR5 inhibitors. Maraviroc ... read more

Cheap pill used to treat HIV could cure Alzheimer’s disease: study

The results are encouraging as Maraviroc - sold under the brand name Selzentry - is already prescribed to patients with the Aids virus. It is hoped repurposing the medication will reverse memory ... read more

An HIV Drug Shows Signs of Guarding Against Dementia

Specifically, the authors repurposed an HIV drug called maraviroc to do so. Maraviroc was approved by the FDA to treat the autoimmune disease in 2007. “We’re very excited about these findings ... read more

Selzentry Oral Solution

Maraviroc 20mg/mL; strawberry flavor. Test all patients for CCR5 tropism prior to initiation. Swallow tabs whole. Concomitant potent CYP3A inhibitors (eg, PIs [except tipranavir/ritonavir ... read more

Side effect(s) of Maraviroc

Review the side-effects of Maraviroc as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of ... read more

Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

This recent preclinical work, coupled with the launch of cinacalcet and maraviroc as the first marketed GPCR allosteric modulators, provide strong validation of the potential clinical utility of ... read more

Bioinformatics prediction of HIV coreceptor usage

Indeed, Pfizer's (New York) small-molecule maraviroc (Selzentry in the United States and Celsentri in the rest of the world) is the first CCR5 blocker to be approved by the FDA and the European ... read more

Types of antiretroviral medications

You would have a test to see if this type of treatment would be effective before starting on it. One CCR5 inhibitor is licensed in Europe: Maraviroc is also known as Celsentri. Fusion inhibitors works ... read more

Ketoconazole Tablets

Caution with concomitant repaglinide, saxagliptin, praziquantel, maraviroc, H 2-blockers, PPIs, and eletriptan (do not use within 72hrs of ketoconazole). Monitor digoxin, phenytoin, carbamazepine ... read more

Drugs chief asks: should the young get priority over elderly patients?

Scotland should open a debate over whether the latest medicines should be prioritised for younger patients over the elderly, the head of ... read more

Maraviroc: A Coreceptor CCR5 Antagonist for Management of HIV Infection

Purpose: The mechanism of action, pharmacology, pharmacokinetics, clinical efficacy, drug interactions, adverse effects, dosage and administration, cost, and role in therapy of maraviroc are reviewed. read more