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Increased cortical advanced glycation end products contribute to ...

Researchers found higher advanced glycation end-product content — associated with decreased bone strength — in the cortical bone of men with vs. without type 2 diabetes, according to data ... read more

Investigating the Effect of Diabetes on Bone Quality via changes in ...

Type 2 diabetes mellitus (T2D) is associated with an increased risk of osteoporotic fractures. Several factors have been identified as being potentially responsible for this increased risk, including ... read more

Advanced glycation end products suppress lysyl oxidase and induce bone ...

Advanced glycation end products (AGEs) are carbohydrate modifications of proteins that include metabolic intermediates formed during the Maillard reaction. AGEs accumulate in long-lived tissues ... read more

Impact of diabetes on bone health and fracture risk highlighted ... - MSN

Cortical porosity and changes in bone material properties—possibly due to advanced glycation end-products (AGEs)—may underlie this fragility. TBS, when used alongside BMD and FRAX, improves ... read more

Increased expression of the receptor for advanced glycation end ...

The receptor for advanced glycation end products (RAGE) has been reported to have a pivotal role in the pathogenesis of Alzheimer’s disease (AD). This study investigated RAGE levels in the ... read more