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Team moves forward in developing a vaccine for the 'zombie drug' xylazine

So, to circumvent this problem, the researchers created a vaccine using a design principle that Janda pioneered, which relies on pairing the drug molecule (called a hapten) with a larger carrier ... read more

Developing a vaccine for the “zombie drug” xylazine

So, to circumvent this problem, the researchers created a vaccine using a design principle that Janda pioneered, which relies on pairing the drug molecule (called a hapten) with a larger carrier ... read more

Designing a Vaccine To Block “Zombie Drug” Xylazine

So, to circumvent this problem, the researchers created a vaccine using a design principle that Janda pioneered, which relies on pairing the drug molecule (called a hapten) with a larger carrier ... read more

Immunotherapy of Allergic Contact Dermatitis

[1] Depending on the status of a person, this may be achieved through: induction of immune tolerance to prevent sensitization; desensitization to eliminate existing hypersensitivity to a hapten or ... read more

Cutaneous and Systemic Hypersensitivity Reactions to Metallic Implants

allowing for hapten formation. These degradation products of the implant may cause increased metal hypersensitivity and implant failure. Those with failed implants have a higher rate of dermal ... read more

Principles of fluorescence in situ hybridization

For indirect labeling, probes are labeled with modified nucleotides that contain a hapten, whereas direct labeling uses nucleotides that have been directly modified to contain a fluorophore. read more

Sarah M. Cheal, PhD

In principle, DOTA-PRIT consists of three sequential administrations of three reagents: (i) the bi-specific Ab construct IgG-scFv (bsAb), which has high specificity and affinity for both a tumor ... read more

Epitope-specific regulation: the elephant in the bathtub

In fact, just the opposite turned out to be true 11: both the magnitude and the affinity of the IgG response to the DNP in the animals immunized with carrier followed by hapten-carrier were well ... read more