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Mechanisms of Fibroblast Growth Factor-2 Modulation of Vascular Endothelial Growth Factor Expression by Osteoblastic Cells

Normal bone growth and repair is dependent on angiogenesis. Fibroblast growth factor-2 (FGF-2), vascular endothelial ... of stimulation with FGF-2 (12.5 ng/ml) in serum-free medium. To investigate dis... read more

Journal of Clinical Oncology

Patients and Methods The expression of key angiogenic genes was studied in bone marrow endothelial cells ... cell line, but upregulates them or is ineffective in nonactive MMECs, MG(u)ECs, NHL-ECs, an... read more

Human limbal biopsy–derived stromal stem cells prevent corneal scarring

1 Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. 2 L V Prasad Eye Institute, Hyderabad 500034, India. 3 Department of Molecular Pharmacology and P... read more

Cornea and Ocular Surface Disease: Application of Cutting-Edge Optometric Research

It is well established that growth factors ... in vivo corneal endothelial pump. Invest Ophthalmol Vis Sci 2012; 53: 2020–9. 40. Nguyen TT, Bonanno JA. Bicarbonate, NBCe1, NHE, and carbonic anhydrase ... read more

Potential Role of Selective COX-2 Inhibitors in Cancer Management

Howe LR, Subbaramaiah K, Chung WJ, et al: Transcriptional activation of cyclooxygenase-2 in Wnt-1-transformed mouse mammary epithelial cells. Cancer Res 59:1572-1577, 1999. 8. Huang M, Sharma S, Mao J... read more

Suffolk County, Mass., funds by Health and Human Services, Department of

Note: For some programs where states do not report where money will be distributed across the state, we do not have the allocation for individual counties. Those programs include: Medicaid, unemployme... read more

Biological Roles of Fibroblast Growth Factor-2

However, during hypoxia, macrophages release FGF-2, and this activity stimulates the growth of hypoxic endothelial ... cells may release FGF-2, which stimulates neovascularization in a paracrine manne... read more

Dr. Paul Sternberg

Dr. Paul Sternberg is an ophthalmologist in Nashville, Tennessee and is affiliated with multiple hospitals in the area, including Tennessee Valley Healthcare System-Nashville and Vanderbilt University ... read more

Distinct microenvironmental cues stimulate divergent TLR4-mediated signaling pathways in macrophages

Both LPS and the FBG domain of tenascin-C stimulate p38, c-Jun N-terminal kinase, and nuclear factor κB signaling ... anti-pp38α antibody (#9211, Cell Signaling Technology) diluted in blocking solutio... read more

Newborn Screening Fact Sheets

Newborn screening fact sheets were last revised ... screening as a public health system; factors contributing to the need for review of the newborn screening system; informed consent; tandem mass spec... read more

Ocular Manifestations of Donohue’s Syndrome

No conjunctival, scleral, or corneal ... and bovine lens epithelium provide an opportunity for studying the biochemical regulation of cell growth and differentiation. The precise regulatory relationsh... read more

The insulin response integrates increased TGF-β signaling through Akt-induced enhancement of cell surface delivery of TGF-β receptors

Departments of Cell and Tissue ... come to appreciate that cells regulate their TGF-β responsiveness by controlling the functional receptor abundance at the cell surface. Activation of the Erk or p38 ... read more