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Murine glomerular transcriptome links endothelial cell-specific molecule-1 deficiency with susceptibility to diabetic nephropathy

With the use of our established protocol[23], we coated the chip with fibronectin (100 μg/mL) for 60 minutes and plated human umbilical vein endothelial cells (HUVEC) (Lonza, Walkersville, MD, USA) into the bMFA. After 4 to 6 hours, we applied shear flow ... read more

Genistein induces alterations of epigenetic modulatory signatures in human cervical cancer cells.

However, the underlying mechanisms have not been fully investigated. In this study, human umbilical vein endothelial cells (HUVE... Genistein suppresses aerobic glycolysis and induces hepatocellular carcinoma cell death. Genistein is a natural isoflavone ... read more

Bioprinting Organs: Researchers Create Less Expensive Bioink Based in 3D Printed Gelatin Hydrogels

Two years ago, a team of researchers with the Queensland University of Technology were working to develop stiffer and more robust hydrogels so they could successfully harvest human cells ... culturing human umbilical vein endothelial cells and human ... read more

Preeclampsia Downregulates MicroRNAs in Fetal Endothelial Cells: Roles of miR-29a/c-3p in Endothelial Function.

Design and Setting: Unpassaged (P0) human umbilical vein endothelial cells (HUVECs) were isolated immediately after cesarean-section delivery from normotensive (NT) and preeclamptic (PE) pregnancies. Differentially expressed miRNAs between P0-HUVECs from ... read more

Octacosanol enhances the proliferation and migration of human umbilical vein endothelial cells via activation of the PI3K/Akt and MAPK/Erk pathways.

we evaluated its effects on the proliferation and migration of human umbilical vein endothelial cells (HUVEC). Cell viability assay using methyl thiazolyl tetrazolium and 5-ethynyl-2'-deoxyuridine revealed that 3.125 μg/ml octacosanol promoted the ... read more

Drop-on-demand bioinks foster angiogenesis

Using a mixed culture of two different vascular cells — human umbilical vein endothelial cells (HUVECs) and human mesenchymal stem cells (hMSCs) — to develop the 3D models, the researchers found that both the printing and UV-crosslinking procedure did ... read more

Revisiting the expression and function of follicle-stimulation hormone receptor in human umbilical vein endothelial cells

Expression of follicle-stimulation hormone receptor (FSHR) is confined to gonads and at low levels to some extragonadal tissues like human umbilical vein endothelial cells (HUVEC). FSH-FSHR signaling was shown to promote HUVEC angiogenesis and thereafter ... read more