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Cell type switch helps colon cancer evade treatment, study suggests

Human colon cancers contain two populations of cancer cells, one at the tumor edge in which the MAPK pathway is highly active (indicated by green staining and the white arrowhead), and one in the cent... read more

The cancer stem cell gamble

“This is really the first time where I'm positioned to help ... cancer stem cells in solid tumors such as breast, colon, brain, and pancreas. Dick and others suggested that these cells, making up perh... read more

'Immunoswitch' particles may be key to more-effective cancer immunotherapy

Those drugs help overcome cancer cells' ability to evade a ... received the "immunoswitch" particles had significantly delayed tumor growth and longer survival compared to those who received the contr... read more

Our top researchers share their ambitions for 2019

It’s clear that the most important thing to do to avoid ... T cell therapies for patients whose disease hasn’t progressed as much. These will really help us to confirm the value of CAR T cell therapie... read more

From whether exercise or dieting will REALLY make you lose weight to the toxic truth behind 'Wine o'clock', TV twin doctors Dr Xand and Chris van Tulleken reveal their anti ...

It is thought that exercise helps keep our bones strong by putting them under stress and subjecting them to jolts and shocks. Each jolt is thought to send signals to bone cells that trigger ... what t... read more

Protein increases signals that protect cancer cells

A cancer-associated ... non-small-cell lung cancer, but it has been shown to be effective in the treatment of many cancers. Researchers in Felsher’s laboratory have been studying the Myc protein for m... read more

Are Some Tumors Just ‘Born to Be Bad’?

Much more remains to be done to validate these findings and extend them to other types of cancer. But the study ... avoid the risks associated with treatment—when it’s safe to do so. [1] Spatial mutat... read more

Dark Clouds Returning For Kitov?

Consensi™ could be the answer for prescribers who avoid ... for the treatment of non-small cell lung cancer (NSCLC). With more than 100 different forms of cancer and drug resistance being a well-known ... read more

Diet and Genes

Pima Indians in the Southwest get type 2 ... known to help prevent heart disease and certain cancers, but only some women seem to show a reduction in breast cancer from drinking it. A study at the Uni... read more

Biologists identify key step in lung cancer evolution

MIT biologists have now identified a major switch ... another cell type that's receiving the niche cues and behaves like a stem cell." While Wnt has been found to drive tumor formation in some other c... read more

The Bellicum Story: What you Need to Know Going Into ASH 2015

Allogeneic transplants have three types of ... infection but avoid GvHD. Thus far, it has been impossible to have both. BPX-501 — How it Works To make BPX-501, Bellicum takes separated mature donor T- ... read more

Cell Carriage, Delivery, and Selective Replication of an Oncolytic Virus in Tumor in Patients

Oncolytic viruses, which preferentially lyse cancer cells and stimulate an antitumor immune response, represent a promising approach to the treatment of cancer. However, how they evade the antiviral . ... read more